Thomas Addison and his disease

Landmark Case Report; Endocrinology
Original Case Report
10.1102/1470-7330.2004.9004
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Thomas Addison and his disease

Thomas Addison’s description of the disease named after him first appears in a book entitled ‘On the constitutional and local effects of disease of the supra-renal capsules’ published by Samuel Highley of 32 Fleet Street London in 1855. This is a superb publication graced with excellent figures as can be seen from the accompanying reprint. Case II from the five cases presented in the book has been selected as being possibly the most representative of the disease, which is seldom nowadays seen in such a florid state since modern diagnostic and therapeutic modalities have become widely available.

Addison’s original description (Case II) is reproduced online here. The paper has been reproduced exactly as it originally appeared in print; the only alteration that has been made is to the layout.
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Editor-in-Chief

Frank Cross
Consultant Vascular and General Surgeon
The London Clinic, UK

Editors

Neil Barnes
Consultant Physician
Barts Health NHS Trust, London, UK
Ali Jawad
Professor of Rheumatology
Barts Health NHS Trust, London, UK

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