Sodium fusidate with simvastatin silencing muscles

Neurology
Case Report
10.1102/1470-5206.2010.0020
10
82-85
Sodium fusidate with simvastatin silencing muscles

A 73-year-old lady became bed bound with progressive generalized weakness 2 weeks after the introduction of sodium fusidate for osteomyelitis. She was already on simvastatin for years. Electromyography showed no spontaneous muscle activity from any of the muscles sampled. The temporal relationship of symptom onset after introduction of fusidic acid and full recovery after cessation of the 2 drugs suggests a serious interaction that deserves wider recognition.

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Editor-in-Chief

Frank Cross
Consultant Vascular and General Surgeon
The London Clinic, UK

Editors

Neil Barnes
Consultant Physician
Barts Health NHS Trust, London, UK
Ali Jawad
Professor of Rheumatology
Barts Health NHS Trust, London, UK

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