Devic’s disease associated with anti-Ro/SSA antibodies

Neurology; Rheumatology
Case Report
10.1102/1470-5206.2010.0024
10
103-106
Devic’s disease associated with anti-Ro/SSA antibodies

Neuromyelitis optica (NMO) and systemic inflammatory diseases are not mutually exclusive. Even when other autoantibodies are present, myelitis extending over 3 vertebral segments with NMO-IgG positivity discloses the diagnosis of NMO. We report the case of an isolated myelitis extending over 6 vertebral segments due to neuromyelitis optica (NMO). Despite the absence of optic nerve involvement, the absence of NMO-IgG in the blood and the presence of symptoms and autoantibodies suggestive of Sjögren syndrome, the diagnosis was founded on spinal magnetic resonance imaging and the detection of NMO-IgG specific antibodies in cerebrospinal fluid.

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Editor-in-Chief

Frank Cross
Consultant Vascular and General Surgeon
The London Clinic, UK

Editors

Neil Barnes
Consultant Physician
Barts Health NHS Trust, London, UK
Ali Jawad
Professor of Rheumatology
Barts Health NHS Trust, London, UK

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