Treatment and follow-up using microscopy and polymerase chain reaction in East African sleeping sickness: a case report

Infection And Immunity
Case Report
10.1102/1470-5206.2011.0003
10
12-16
Treatment and follow-up using microscopy and polymerase chain reaction in East African sleeping sickness: a case report

We report a case of East African trypanosomiasis in a 26-year-old traveler returning from Tanzania, including a series of pictures of the progression of the inoculation chancre. Trypanosoma brucei rhodesiense-specific DNA was detected in the blood until 8 days after treatment. We hypothesize that the previously observed suramin toxicity may be an immunological response to parasite debris, produced as they are killed by the treatment.

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Editor-in-Chief

Frank Cross
Consultant Vascular and General Surgeon
The London Clinic, UK

Editors

Neil Barnes
Consultant Physician
Barts Health NHS Trust, London, UK
Ali Jawad
Professor of Rheumatology
Barts Health NHS Trust, London, UK

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