A 4-year-old boy with beta-thalassemia major who underwent a successful bone marrow transplant (BMT), presented with a necrotic looking scalp lesion. Debridement was initially suggested but a punch biopsy showed Aspergillus fumigatus. Antifungal therapy was commenced and the lesion healed with minimal scarring. Invasive fungal infections are a major cause of morbidity and mortality in immune-compromised patients. Invasive aspergillosis (IA) has been on the increase since 1980. The most common manifestation of IA after BMT is invasive pulmonary aspergillosis. Primary cutaneous aspergillosis is extremely rare in the paediatric BMT population. There is scanty information regarding management of these lesions in children. Excision and skin grafting of these lesions is not the ideal treatment in the immune compromised and healing by secondary intention may leave a large scar. Suspicious skin lesions should not be subjected to immediate wide surgical debridement leaving a large uncovered area with subsequent extensive scarring and failure to respond to skin grafting.