Acquired haemophilia in an elderly woman

Emergency Medicine And Surgery; Haematology
Case Report
10.1102/1470-5206.2015.0002
15
4-6
Acquired haemophilia in an elderly woman

Acquired haemophilia is a rare autoimmune condition with an annual incidence of one per million. It is more common in the elderly and is associated with the presence of anti-factor VIII IgG antibodies. Most cases are idiopathic but there are also known associations with malignancy, other autoimmune diseases and drug interactions. As aging itself is not a cause of changes in range of coagulation tests (prothrombin time, activated partial thrombin time or thrombin time), platelet count or fibrinogen levels, an abnormality in these should prompt the physician to search for a cause of the change. The case of an elderly lady who presented with severe soft tissue bleeding secondary to factor VIII inhibitor deficiency is presented in this report.

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Editor-in-Chief

Frank Cross
Consultant Vascular and General Surgeon
The London Clinic, UK

Editors

Neil Barnes
Consultant Physician
Barts Health NHS Trust, London, UK
Ali Jawad
Professor of Rheumatology
Barts Health NHS Trust, London, UK

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